ea0022p647 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010
Goncalves Ana
, Batista Fernando
, do Carmo Isabel
Introduction: Cushings syndrome results from increased or aberrant expression of ACTH, CHR, or neuroendocrine receptors that leads to uncontrolled hypersecretion of cortisol. The most common cause is ACTH-secreting pituitary adenomas. Alternatively, the glucocorticoid excess may be due to adrenal neoplasia or to ectopic ACTH secreting tumors. There are rare reports of patients with a meningioma secreting CRH presenting paraneoplasic Cushings syndrome.<p ...